Eisen A. (ed.) Clinical Neurophysiology of Motor Neuron Diseases

Academic Press, Elsevier, 2004. — 700 p.Overview
Comparative anatomy of the motor system: differences in the organization of corticospinal control in different species
Developmental aspects of corticospinal projections
Principles of corticospinal system organization and function
Molecular mechanisms regulating motor neuron development and degeneration
Physiology of the motor neuron and the motor unit
Cytopathology of the motor neuron
Genetics of amyotrophic lateral sclerosis
Neuroimaging in amyotrophic lateral sclerosis
Animal models of motor neuron death
Needle electromyography
Peripheral nerve conduction studies and neuromuscular junction testing
Motor unit number estimates
Magnetic stimulation and central conduction time
Evoked potentials in amyotrophic lateral sclerosis
The triple stimulation technique
Cortical threshold and excitability measurements
Spinal and long-latency reflexes
Single unit recordings – peristimulus time histograms (PSTHs)
Threshold electrotonus and the assessment of nerve excitability in amyotrophic lateral sclerosis
Other forms of spinal muscular atrophies
Arthrogryposis multiplex and related congenital disorders
Spinobulbar muscular atrophy (Kennedy's disease)
Late muscular sequelae after poliomyelitis
Toxic motor neuronopathies and neuropathies
Motor neuron disorders with other diseases and exposures
Classic Charcot amyotrophic lateral sclerosis
Electrophysiological evaluation of oropharyngeal dysphagia in ALS
Electrodiagnostic assessment of respiratory dysfunction in motor neuron disease
Assessment of autonomic function in motor neuron diseases
Neurophysiology of hereditary amyotrophic lateral sclerosis
Autosomal recessive juvenile amyotrophic lateral sclerosis
Paraneoplastic motor neuron disease
Multifocal motor neuropathy
Focal amyotrophies of the upper and lower limbs
Primary lateral sclerosis
Hereditary spastic paraplegia
Hereditary ataxias
Konzo
Application of clinical neurophysiology to clinical trials involving motor neuron diseases
The role of clinical neurophysiology inmotor neuron diseases: where next?
Index